Studying Nocturnal Blood Pressure Patterns and Levels and Obstructive Sleep Apnea: Clinical Implications and Technical Solution

EasyChair Preprint 3549

Abstract

Background Beside specific consequences, obstructive sleep apnea (OSA) has been described as a novel and major risk factor of high blood pressure (BP), cardiovascular complications and organ damage. However, the causal relationship between OSA and hypertension need to be further studied and characterized. Ambulatory blood pressure monitoring (ABPM), which is now considered as part of standard of care in management of hypertension, measures person's BP at regular intervals including nighttime period. The study aims to initially describe possible association between BP, especially nighttime BP, and OSA. Methodology The study was conducted on both inpatient and outpatient subjects who had never been diagnosed with or treated for hypertension but having clear or dim notion of fluctuating clinic or self-measured home BP. Respiratory polysomnography (rPSG) indicated, when appropriate, led to the identification of two subgroups (with/without OSA). The 24-hour ABPM was then indicated to perform on subjects of both subgroups. Both exploratory techniques are non-invasive and have their own indication in clinical contexts. Results In two subgroup of 12 and 19 patients with or without OSA respectively, ABPM reported initially a higher proportion of isolated nocturnal hypertension, non-dipper nocturnal BP patterns or nighttime BP surges in subgroup of patients with OSA compared that recorded in non-OSA control subgroup. Conclusion and Discussion Initial study results suggest the patterns of nocturnal BP in patients with- and without OSA. Nocturnal BP pattern appears to have critical and increasing importance, which could only be achieved (for now) by costly ABPM Holter systems. Close collaboration with an BME team to permit the transformation of automated tensionmeters with timer to become devices functionally similar to ABPM Holter systems is medically sound and cost-effective.

Keyphrases: Hypertension, OSA, ambulatory blood pressure monitoring (ABPM), nocturnal BP pattern, respiratory polysomnography (rPSG)

@booklet{EasyChair:3549,
  author    = {Hong Lien Nguyen Thi and Khuyen Pham Thi and Bich Hue Bui Thi and Thu Hang Tran Thi and Minh Thu Vu Thi and Khai Nguyen Van and Linh Pham Van},
  title     = {Studying Nocturnal Blood Pressure Patterns and Levels and Obstructive Sleep Apnea: Clinical Implications and Technical Solution},
  howpublished = {EasyChair Preprint 3549},
  year      = {EasyChair, 2020}}