Download PDFOpen PDF in browserHigh-Flow Nasal Oxygen Therapy in Pediatric Respiratory Distress: Clinical Outcomes and Best PracticesEasyChair Preprint 136859 pages•Date: June 17, 2024AbstractHigh-flow nasal oxygen therapy (HFNO) has emerged as a promising intervention in managing pediatric respiratory distress, offering a non-invasive alternative to traditional methods such as mechanical ventilation. This paper reviews the current literature on HFNO therapy in pediatric patients, focusing on its clinical outcomes and best practices. A systematic review of studies published between 2010 and 2024 was conducted, highlighting key findings regarding the efficacy and safety of HFNO therapy. The review discusses the physiological mechanisms of HFNO, its indications, contraindications, and practical considerations in pediatric settings. Furthermore, it examines the impact of HFNO on patient outcomes, including respiratory rate, oxygenation, work of breathing, and rates of intubation and escalation of care. Additionally, the review identifies best practices for implementing HFNO therapy in pediatric respiratory distress, including optimal flow rates, interface selection, monitoring parameters, and weaning strategies. Finally, the paper discusses future directions for research and clinical practice, emphasizing the need for standardized protocols and further studies to elucidate the long-term effects and cost-effectiveness of HFNO therapy in pediatric populations. Keyphrases: High-flow nasal oxygen therapy (HFNO), Pediatric, mechanical ventilation
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